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A category of diabetes drugs, which come with the best-selling drug Ozempic, are related to a discounted chance of positive obesity-related cancers, in keeping with a learn about launched Friday.
Printed within the magazine JAMA, the learn about in comparison sufferers with Kind 2 diabetes who had been handled with insulin as opposed to sufferers who got a category of drug referred to as GLP-1 agonists, like Ozempic, between 2005 and 2018.
The researchers discovered that the sufferers who won GLP-1 agonists had a considerably decrease chance of creating 10 out of 13 cancers studied, together with kidney, pancreatic, esophageal, ovarian, liver and colorectal most cancers.
A few of the cancers which noticed no important exchange in chance had been thyroid most cancers and breast most cancers in postmenopausal girls.
“Weight problems is widely recognized to be related to no less than 13 most cancers varieties,” learn about writer Rong Xu mentioned in an e mail to AFP.
“Our learn about supplies proof that GLP-1RAs dangle promise in breaking the hyperlink between weight problems and most cancers,” Xu mentioned.
A few of the medicine studied had been semaglutide—commercially offered as Ozempic—in addition to liraglutide and others. Ozempic was once licensed in america in 2017.
GLP-1 agonists had been round for roughly twenty years, however a brand new technology of those medicine, amongst them Ozempic, has been popularized for his or her extra important weight reduction results.
Xu steered that the protecting advantages demonstrated within the learn about would possibly inspire docs to prescribe GLP-1 remedies for diabetes sufferers as a substitute of different drugs like insulin.
Additional info:
Lindsey Wang et al, Glucagon-Like Peptide 1 Receptor Agonists and 13 Weight problems-Related Cancers in Sufferers With Kind 2 Diabetes, JAMA Community Open (2024). DOI: 10.1001/jamanetworkopen.2024.21305
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