How a Lucky Break Fueled Eli Lilly’s $600 Billion Weight-Loss Empire – The Gentleman Report | World | Business | Science | Technology | Health
Today: Mar 30, 2025

How a Lucky Break Fueled Eli Lilly’s $600 Billion Weight-Loss Empire

How a Lucky Break Fueled Eli Lilly’s 0 Billion Weight-Loss Empire
January 27, 2024

## How Eli Lilly’s Weight-Loss Empire Started

If only Eli Lilly & Co. had heeded Richard DiMarchi’s advice, it could have led the $80 billion weight-loss drug market. Three decades ago, DiMarchi, a scientist at the Indianapolis-based drugmaker, was researching a gut hormone called glucagon-like peptide-1. In a small trial, he demonstrated that an infusion of the hormone led to weight loss in humans. The potential was so significant that he and a colleague filed a patent. Should Lilly have developed a product using this technology, it would have had exclusive rights to sell the weight management treatment for at least a decade.

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