A best physician has published an alarming new symptom he has noticed emerge amongst Ozempic sufferers. Dr Daniel Rosen, who’s a surgeon and weight problems medication specialist based totally out of New York, says a ‘reputable quantity’ of his sufferers have evolved a situation known as allodynia, or a allergy to ache.Dr Rosen says because of this even dressed in clothes can really feel painful, as can the ‘wind blowing for your pores and skin.’Some other folks describe the feeling on their pores and skin as being like dangerous sunburn, with the feeling of contact triggering a pointy, stinging or burning ache. The burden loss professional says some sufferers the use of GLP-1 medication similar to Ozempic and Mounjaro have evolved excessive sensitivity on their shoulders, thighs and again. He says he has heard of the situation creating amongst the ones the use of semaglutide (the generic identify for Ozempic) within the medical neighborhood, however he has no longer but noticed experiences of it amongst the ones on terzepatite (higher recognized by way of the logo names Zepbound and Mounjaro).From his enjoy, Dr Rosen says he has noticed essentially the most instances of allodynia in sufferers who had been on upper doses of terzepatite. He suspects that weight reduction medicine medication are inflicting pores and skin nerve sensitivity ‘by hook or by crook’ however there isn’t sufficient analysis round this facet impact to understand precisely why this occurs.
Dr Daniel Rosen, who’s a surgeon and weight problems medication specialist based totally out of New York, says a ‘reputable quantity’ of his sufferers have evolved a situation known as allodynia
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The Cleveland Health center highlights that there are 3 forms of allodynia. Dynamic allodynia reasons ache from an object shifting throughout your pores and skin, whilst tactile allodynia reasons ache from any quantity of force carried out to the surface.The 3rd variation is thermal allodynia, the place a light exchange in temperature – like shifting from indoors to open air – may cause any person to really feel ache. To lend a hand sufferers who’ve evolved allodynia, Dr Rosen lowered their weight reduction medicine. He says this noticed the indicators disappear instantly or in some instances, the situation went away extra steadily. Dr Anastassia Amaro, who’s a scientific director and weight reduction specialist at Penn Drugs, says she has additionally noticed a equivalent facet impact amongst her sufferers on weight reduction medication. In a podcast Q&A consultation in January 2024, she published: ‘One attention-grabbing facet impact that I have noticed not too long ago is allodynia. ‘So other folks increase that unsightly, painful [tingling or numb] form of pores and skin sensation, in particular on semaglutide. ‘I’ve no longer encountered it but on tirzepatide, however semaglutide, sure. A minimum of two instances are in entrance of my eyes. Dr Rosen says allodynia implies that even dressed in clothes can really feel painful, as can the ‘wind blowing for your pores and skin”One answered to dose aid and some other one held it for just a little bit, after which I believe we switched to tirzepatide, and I am but to look how that is going. So, and we will be able to more than likely see extra.’Recently, there are not any research having a look on the hyperlink between weight reduction medication and allodynia and it’s not indexed by way of the FDA as an authentic facet impact. Whilst Dr Rosen says allodynia is uncomfortable, he does not suppose the facet impact is one thing this is ‘very regarding’ except it turns into ‘bothersome’.Or even then, he says, sufferers will have to weigh up whether it is ‘price getting off the meds and type of sacrificing the certain advantages of the meds’.He notes that once his sufferers have lowered their weight reduction medicine and slowly larger it once more, they have got no longer noticed their allodynia signs go back. For individuals who are on weight reduction medication, Dr Rosen warns that it’s ‘simply one thing to pay attention to [and ] in case you see it, speak about it together with your physician’.